A Study on Osmotic Fragility of Erythrocytes of Tuberculosis Patient’s Blood

The paper presents the data on percent lysis of hemoglobin in Tuberculosis patient’s blood. Osmotic fragility is the ability of RBC’s to resist rupture (lysis) in hypotonic saline. The degree of hemolysis can be estimated by measuring the colour intensity of the supernant in a spectrophotometer at 540nm and comparing it with 100%. The task is to examine the relationship between the extent of hemolysis and osmolarity of the medium in which the erythrocytes are suspended. The percent lysis of erythrocytes of tuberculosis patient’s blood is significantly more than that of normal. It means erythrocytes of tuberculosis patients are more fragilie than normal.